[1] Dethlefsen L, Relman DA. Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation. Proceedings of the National Academy of Sciences. 2011;108(Suppl 1):4554-4561. doi:10.1073/pnas.1000087107
[2] Faye AS, Allin KH, Iversen AT, et al. Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study. Gut. 2023;72(4):663-670. doi:10.1136/gutjnl-2022-327845
[3] Hrncir T. Gut microbiota dysbiosis: triggers, consequences, diagnostic and therapeutic options. Microorganisms. 2022;10(3):578. doi:10.3390/microorganisms10030578. See also: Ramirez J, et al. Antibiotics as major disruptors of gut microbiota. Frontiers in Cellular and Infection Microbiology. 2020;10:572912.
[4] Tulstrup MVL, et al. Antibiotic treatment affects intestinal permeability and gut microbial composition in Wistar rats dependent on antibiotic class. PLOS ONE. 2015;10(12):e0144854. doi:10.1371/journal.pone.0144854
[5] Jernberg C, et al. Long-term ecological impacts of antibiotic administration on the human intestinal microbiota. The ISME Journal. 2007;1(1):56-66. doi:10.1038/ismej.2007.3
[6] Valenti P, Antonini G. Lactoferrin: an important host defence against microbial and viral attack. Cellular and Molecular Life Sciences. 2005;62:2576-2587. See also: Orsi N. The antimicrobial activity of lactoferrin: current status and perspectives. Biometals. 2004;17(3):189-196.
[7] Ulfman LH, et al. Effects of bovine immunoglobulins on immune function, allergy, and infection. Frontiers in Nutrition. 2018;5:52. doi:10.3389/fnut.2018.00052
[8] Superti F. Lactoferrin from bovine milk: a protective companion for life. Nutrients. 2020;12(9):2562. See also: Oda H, et al. The impact of lactoferrin on the growth of intestinal inhabitant bacteria. International Journal of Molecular Sciences. 2019;20(20):4706.
[9] Davoodvandi A, et al. Bovine colostrum in increased intestinal permeability in healthy athletes and patients: a meta-analysis of randomized clinical trials. Digestive Diseases and Sciences. 2024;69:580-591. doi:10.1007/s10620-023-08219-2
[10] Marchbank T, et al. The nutriceutical bovine colostrum truncates the increase in gut permeability caused by heavy exercise in athletes. American Journal of Physiology—Gastrointestinal and Liver Physiology. 2011;300(3):G477-G484. doi:10.1152/ajpgi.00281.2010
[11] Playford RJ, et al. Colostrum and milk-derived peptide growth factors for the treatment of gastrointestinal disorders. The American Journal of Clinical Nutrition. 2000;72(1):5-14. doi:10.1093/ajcn/72.1.5
[12] Eslamian G, et al. Effects of early enteral bovine colostrum supplementation on intestinal permeability in critically ill patients: a randomized, double-blind, placebo-controlled study. Nutrition. 2019;60:106-111. doi:10.1016/j.nut.2018.10.013